[Treatment of chronic obstructive pulmonary disease and emphysema]. / Metody lecheniya khronicheskoi obstruktivnoi bolezni i emfizemy legkikh.

We summarized the available data on therapeutic, surgical and endoscopic treatment of chronic obstructive pulmonary disease and emphysema that may be used like a bridge to lung transplantation. Treatment of chronic obstructive pulmonary disease and emphysema is expensive. Certain limitations in lung transplantation make to create new methods of treatment of severe emphysema. However, one should be ready for possible complications and carefully select patients for certain treatment to avoid false negative results. Reducing costs or developing cheaper treatments is important for the future and availability of care. The risks and complications associated with surgical treatment of emphysema can make endoscopic surgery preferable for these patients, and this undoubtedly requires further research.

[Surgical treatment of varicosity-altered tributaries of saphenous veins].

A total of 469 patients presenting with lower-limb varicose disease were operated on at Municipal Clinical Hospital No 79 of the Chair of Hospital Surgery No 2 of the I.M. Sechenov First Moscow State Medical University over the period from 2008 to 2011. The tributaries of varicose veins were removed by means of miniphlebectomy according to the Muller technique, the Narat technique, with the use of a cryoprobe and an original-design vein extractor. The main method of removing tributaries is currently miniphlebectomy by the Muller technique. However, removal of the tributaries over 10 mm in diameter by the Muller s technique was associated with a skin tear in the site of the puncture, which healed with the formation of a hypertrophic scar. Miniphlebectomy of tributaries measuring less than 10 mm in diameter with the signs of previously endured phlebitis is accompanied, as a rule, by a rupture of the venous wall in the form of phlebosclerosis and a commissural process with the underlying cellular tissue. Phlebectomy by the Narat s technique was predominantly performed for removal of short tributaries from the altered paravasal cellular tissue. The method of cryophlebectomy was used by means of intravasal or paravasal insertion of the probe. A vein extractor was used to remove the tributaries form the altered cellular tissue at a distance of up to 20 cm. The choice of an optimal method of treatment for varicosity-altered tributaries makes it possible to decrease the complications rate and to obtain good cosmetic outcomes.

[Plasma fibronectin in complicated forms of respiratory viral infections in young children]. / Plazmennyi fibronektin pri oslozhnennykh formakh respiratornykh virusnykh infektsii u detei rannego vozrasta.

As many as 89 infants with acute respiratory viral infections (ARVI) were examined to establish a decrease of the levels of immunochemical and bioactive fibronectin, seen during the marked clinical manifestations of the disease. Changes in the level of fibronectin in the course of ARVI are reversible in nature, being related to the intensity of the general toxic manifestations. Measurements of bioactive fibronectin are most informative for assessing the degree of intoxication. Profound and long-term reduction of the level of bioactive fibronectin may be seen in grave focal confluent and polysegmental pneumonia.